Contents
24 February 2017
Vol 355, Issue 6327
Vol 355, Issue 6327
Contents
This Week in Science
Editorial
Editors' Choice
Departments
Products & Materials
- New Products
A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
In Brief
In Depth
- Planet Earth to get a daily selfie
Researchers await data from the satellite company Planet, which has launched a flotilla of tiny eyes in the sky that will soon image the entire globe every day.
- Publication ban upends NIH lab, collaborators
Citing protocol violations, institute won't allow use of 25 years of data.
- Eastern Europe's laser centers will debut without a star
ELI's plans for a 200-petawatt laser quietly postponed.
- CRISPR patent ruling leaves license holders scrambling
Widely anticipated decision affirms Broad Institute's claim to genome editing in human cells, but the battle is not over.
- California rains put spotlight on atmospheric rivers
Forecasts of moisture conduits could aid water managers.
Feature
Working Life
Letters
Books et al.
- Deadly force
A timely tome calls for more research on police killings and departmental training that emphasizes that “lives matter”
- In defense of basic research
A 1939 essay resonates today, persuasively advocating for science for science's sake
Policy Forum
- To slow or not? Challenges in subsecond networks
Advancing understanding of extreme behaviors beyond human response times is vital to our electronics-driven world
Perspectives
- A Mesozoic aviary
Biomechanical models are key to understanding how dinosaurs experimented with different ways of flying
- Quantifying protein (dis)order
A study of bacteria, yeast, and mammalian cells maps the melting behavior of cellular proteins
- Why tolerance invites resistance
Bacteria that encounter antibiotics first become tolerant and then resistant to them
- Molecular stitches for enhanced recycling of packaging
An additive creates tough blends from waste polyethylene and polypropylene
- Hematopoietic stem cells gone rogue
Somatic mutations in hematopoietic stem cells aggravate cardiovascular disease
- Thomas Crombie Schelling (1921–2016)
A pioneering game theorist who made the world a safer place
Association Affairs
Research Articles
- The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport
Charge transfer along DNA can regulate the activity of an enzyme involved in eukaryotic DNA replication.
- Cell-wide analysis of protein thermal unfolding reveals determinants of thermostability
Proteomic analysis provides insight into the molecular and evolutionary bases of proteins and proteome thermal stability.
Review
Reports
- Combining polyethylene and polypropylene: Enhanced performance with PE/iPP multiblock polymers
Polyethylene/isotactic polypropylene multiblock copolymers enable welding of composites of the two immiscible polymers.
- An accreting pulsar with extreme properties drives an ultraluminous x-ray source in NGC 5907
An ultraluminous x-ray source in NGC 5907 is a spinning neutron star with a complex magnetic field.
- Predicting human olfactory perception from chemical features of odor molecules
Results of a crowdsourcing competition show that it is possible to accurately predict and reverse-engineer the smell of a molecule.
- Antibiotic tolerance facilitates the evolution of resistance
Tolerance to antibiotics is often overlooked in the clinic, but tolerance drives the rapid evolution of resistance.
- The cytotoxic Staphylococcus aureus PSMα3 reveals a cross-α amyloid-like fibril
Fibrillation-dependent cytotoxicity of PSMα3 functional amyloid is encoded by an unusual cross-α peptide architecture.
- Bumblebees show cognitive flexibility by improving on an observed complex behavior
Bumblebees will use a ball as a tool to obtain a reward.
- Optical control of cell signaling by single-chain photoswitchable kinases
Single-chain photoswitchable kinases based on engineered photodissociable proteins enable fine control of kinase activity.
- Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice
Bone marrow deficient in a gene frequently mutated in blood cells of elderly humans promotes atherosclerosis in mice.
Technical Comments
About The Cover
COVER Three-dimensionally visualized atomic force microscopy (AFM) images of a colloidal probe decorated with zirconia clusters (top) approaching a clusterassembled carbon film (bottom). The properties of cluster-assembled surfaces are actively being investigated for a variety of applications. The Gordon Research Conference on Clusters & Nanostructures will be held from 9 to 14 July 2017 in South Hadley, Massachusetts. See page 848 for the Gordon Research Conference schedule and preliminary programs.
AFM images: F. Borghi, M. Chighizola, L. Marfori/Interdisciplinary Centre for Nanostructured Materials and Interfaces (CIMaINa), University of Milano, Italy; Rendering: Valerie Altounian/Science