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2C-G-N

From Wikipedia, the free encyclopedia
2C-G-N
Clinical data
Other names2C-G-NPH; 2C-NPH; 1,4-Dimethoxynaphthyl-2-ethylamine
Routes of
administration
Oral[1]
Drug classPsychoactive drug; Stimulant; Antidepressant
ATC code
  • None
Pharmacokinetic data
Duration of action20–30 hours[1]
Identifiers
  • 2-(1,4-dimethoxynaphthalen-2-yl)ethanamine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H17NO2
Molar mass231.295 g·mol−1
3D model (JSmol)
  • COC1=CC(=C(C2=CC=CC=C21)OC)CCN
  • InChI=1S/C14H17NO2/c1-16-13-9-10(7-8-15)14(17-2)12-6-4-3-5-11(12)13/h3-6,9H,7-8,15H2,1-2H3
  • Key:VKWQEEWEGKDTDE-UHFFFAOYSA-N

2C-G-N, or 2C-G-NPH, also known as 1,4-dimethoxynaphthyl-2-ethylamine, is a psychoactive drug of the phenethylamine, 2C, and naphthylethylamine families.[1] It is the derivative of 2C-G in which the 3,4-dimethyl groups have been extended and connected to form a second benzene ring and hence has a 2-naphthalene ring system.[1] In his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, Alexander Shulgin lists 2C-G-N's dose as 20 to 40 mg orally and its duration as 20 to 30 hours.[1][2][3] The effects of the drug were reported to include some amphetamine-like stimulation, some possible antidepressant-like effects, "not much psychedelic" but "something really going on anyway", faint uneasiness, and "not as friendly" of effects as other 2C-G compounds.[1] Its activity was described as "on the wane" compared to other 2C-G drugs and as lasting "too long".[1] The chemical synthesis of 2C-G-N has been described.[1] The drug was first described in the literature by Shulgin in PiHKAL in 1991.[1]

See also

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References

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  1. ^ a b c d e f g h i Shulgin, Alexander; Shulgin, Ann (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. https://www.erowid.org/library/books_online/pihkal/pihkal031.shtml
  2. ^ Jacob P, Shulgin AT (1994). "Structure-Activity Relationships of the Classic Hallucinogens and Their Analogs". In Lin GC, Glennon RA (eds.). Hallucinogens: An Update (PDF). National Institute on Drug Abuse Research Monograph Series. Vol. 146. National Institute on Drug Abuse. pp. 74–91. PMID 8742795. Archived from the original on 13 July 2025.
  3. ^ Shulgin AT (2003). "Basic Pharmacology and Effects". In Laing RR (ed.). Hallucinogens: A Forensic Drug Handbook. Forensic Drug Handbook Series. Elsevier Science. pp. 67–137. ISBN 978-0-12-433951-4. Archived from the original on 13 July 2025.
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