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Speech as a biomarker

Perhaps there could be details on idiolects and also speech as a predictor for diseases as mentioned is the following articles (an area of pretty active research apparently but it could at least deserve a mention). I understand Wikipedia is not a literature review and writes what is general consensus, but this seems pretty active. Plus, perhaps one could also mention how modern technology has affected language and speech patterns.

A novel fusion architecture for detecting Parkinson’s Disease using semi-supervised speech embeddings

https://www.nature.com/articles/s41531-025-00956-7

(June 2025)

https://pmc.ncbi.nlm.nih.gov/articles/PMC8772820/

Speech- and Language-Based Classification of Alzheimer’s Disease: A Systematic Review

(43 citations, Jan 2022)

Speech as a Biomarker for Disease Detection

https://arxiv.org/html/2409.10230v1#abstract

(8 citations, Sep 2024)

Machine Learning-Driven Speech Biomarker Analysis: A Novel Approach for Detecting Cognitive Decline in Older Adults

https://alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/alz.094259

(Jan 2025)

Connected Speech in Neurodegenerative Language Disorders: A Review

https://pmc.ncbi.nlm.nih.gov/articles/PMC5337522/

(115 citations, Mar 2017)

Language impairments in people with autoimmune neurological diseases: A scoping review

https://www.sciencedirect.com/science/article/pii/S0021992423000680

(8 cites, Dec 2023)

Speech and language biomarkers for Parkinson’s disease prediction, early diagnosis and progression

https://www.nature.com/articles/s41531-025-00913-4

(7 cites, Mar 2025)

Speech dysfunction, cognition, and Parkinson’s disease

https://pmc.ncbi.nlm.nih.gov/articles/PMC11321444/

(13 cites, Feb 2022)

Linguistic changes in spontaneous speech for detecting Parkinson’s disease using large language models

https://pmc.ncbi.nlm.nih.gov/articles/PMC11809853/

(Feb 2025)

Speech deficits in serious mental illness: a cognitive resource issue?

https://pubmed.ncbi.nlm.nih.gov/25464920/

(46 cites, Dec 2014)

Evaluation of Speech-Based Digital Biomarkers: Review and Recommendations

https://pmc.ncbi.nlm.nih.gov/articles/PMC7670321/

(60 cites, Oct 2020)

Speech as a Biomarker for Depression

https://www.eurekaselect.com/article/119378

(61 cites, Feb 2023)

Speech as a Biomarker: Opportunities, Interpretability, and Challenges

https://www.researchgate.net/publication/357771804_Speech_as_a_Biomarker_Opportunities_Interpretability_and_Challenges

(56 cites, Jan 2022)

Evaluation of Speech-Based Digital Biomarkers: Review and Recommendations Open Access

https://pubmed.ncbi.nlm.nih.gov/33251474/

(147 cites, Oct 2020)

The voice of depression: speech features as biomarkers for major depressive disorder

https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-024-06253-6

(12 cites, Nov 2024)

Articulatory precision from connected speech as a marker of cognitive decline in Alzheimer’s disease risk-enriched cohorts

https://pmc.ncbi.nlm.nih.gov/articles/PMC11798706/

(Feb 2025)

LANGUAGE AND DEMENTIA: NEUROPSYCHOLOGICAL ASPECTS

https://pmc.ncbi.nlm.nih.gov/articles/PMC2976058/

(32 cites, Jan 2008)

Speaking in Alzheimer’s Disease, is That an Early Sign? Importance of Changes in Language Abilities in Alzheimer’s Disease

https://app.dimensions.ai/details/publication/pub.1044421552

(183 cites, Oct 2015)

Linguistic changes in neurodegenerative diseases relate to clinical symptoms

https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1373341/full

(2 cites, Mar 2024)

https://pmc.ncbi.nlm.nih.gov/articles/PMC10583496/

Lexical Speech Features of Spontaneous Speech in Older Persons With and Without Cognitive Impairment: Reliability Analysis

(2 cites, Oct 2023) 123 GenericUser (talk) 05:47, 9 August 2025 (UTC)[reply]