

That “door” is what health experts refer to as the early detection window, and in India, sadly, half of all people with diabetes miss out on it.

Do you know that, for many people, the journey with diabetes starts quietly years before any test results show up? Slowly and steadily, the blood sugar begins to rise, and gentle changes occur within the blood vessels,1 nerves,2 and organs.3
At first, nothing feels out of place. Life goes on, juggling deadlines, family commitments, weddings to attend, and late-night meals with friends, without a hint of what’s to come.
Then, one day, someone goes to the clinic complaining of some complications affecting some organ, like the kidneys or liver, or even the heart. After tests, the diagnosis is diabetes, and not the early stage, but the type that has already caused damage.
Why warning signs go unheard
It’s natural to feel okay when you’re not experiencing symptoms. However, with diabetes, this feeling can sometimes be misleading and dangerous. Many people in India are diagnosed late for reasons like:
- Invisible markers: Early diabetes rarely causes pain or obvious discomfort.4 Weight is a primary target in diabetes, which is often overlooked.
- Low priority for preventive care: Annual health check-ups are not regularly scheduled.5
- Busy urban lifestyles: Long work hours and fast food habits push health off the priority list.6
- Genetic susceptibility: South Asians tend to develop diabetes earlier and experience a faster progression compared to other populations.7

When diagnosis is delayed, chances are high that the body has often been battling high blood sugar for years. This can set off a chain reaction, including:
- Strain on the kidneys that can progress to chronic disease.8
- Nerve damage in the feet, thereby increasing the risk of infections.9
- Narrowing of arteries, raising the risk of heart attack and stroke.10
The natural partners in your health: GLP-1 and insulin hormone
Insulin is an essential hormone. It helps your body turn food into energy and manages your blood sugar levels. If you have diabetes, your body can’t make enough insulin or can’t use it properly.
But it’s worth pausing to talk about a little-known ally your body already has: GLP-1 (glucagon-like peptide-1). It is a hormone made in your intestine and released after meals. It helps your body work smarter by: 10-12
- Prompting insulin release when needed
- Slowing digestion so blood sugar rises more steadily
- Signalling fullness to help prevent overeating
- Supporting healthy blood vessels and reducing inflammation
Catching diabetes before it catches you
The good news is that the missed window doesn’t have to remain missed. Here’s how you can keep it open longer:
- Get screened if you have risk factors such as family history, excess weight, a sedentary lifestyle, or high blood pressure.5, 13, 14
- Know your key health numbers, including blood sugar, cholesterol, and blood pressure.15
- Make preventive checkups a regular habit rather than an afterthought.5
- Pay attention to subtle signs like fatigue, frequent thirst, or blurry vision. They are worth investigating.16
- Stay consistent with your health efforts, as maintaining health requires ongoing commitment over months and years, not just occasional actions.5

Diabetes may be common in India, but late diagnosis doesn’t have to be. The earlier it’s found, the more control you have over your future. The later it’s found, the more you’re reacting instead of preventing.
The window is open right now, but will you walk through it before it starts to close?
References
- Rask-Madsen C, King GL. Vascular complications of diabetes: mechanisms of injury and protective factors. Cell metabolism. 2013;17(1):20-33.
- Yagihashi S, Mizukami H, Sugimoto K. Mechanism of diabetic neuropathy: Where are we now and where to go? Journal of diabetes investigation. 2011;2(1):18-32.
- Tomic D, Shaw JE, Magliano DJ. The burden and risks of emerging complications of diabetes mellitus. Nature Reviews Endocrinology. 2022;18(9):525-39.
- Dong W, Zhang S, Yan S, Zhao Z, Zhang Z, Gu W. Clinical characteristics of patients with early-onset diabetes mellitus: a single-center retrospective study. BMC Endocrine Disorders. 2023;23(1):216.
- Organization WH. Diabetes Geneva: World; 2024 [
- Baek S-U, Won J-U, Yoon J-H. Long Working Hours and Unhealthy Lifestyles of Workers: A Protocol for a Scoping Review. 2024;4(4):431-9.
- Hodgson S, Williamson A, Bigossi M, Stow D, Jacobs BM, Samuel M, et al. Genetic basis of early onset and progression of type 2 diabetes in South Asians. Nature medicine. 2025;31(1):323-31.
- Jha R, Lopez-Trevino S, Kankanamalage HR, Jha JC. Diabetes and Renal Complications: An Overview on Pathophysiology, Biomarkers and Therapeutic Interventions. 2024;12(5):1098.
- Staehelin Jensen T. The pathogenesis of painful diabetic neuropathy and clinical presentation. Diabetes Research and Clinical Practice. 2023;206:110753.
- Huber H, Schieren A, Holst JJ, Simon MC. Dietary impact on fasting and stimulated GLP-1 secretion in different metabolic conditions - a narrative review. The American journal of clinical nutrition. 2024;119(3):599-627.
- van Bloemendaal L, RG IJ, Ten Kulve JS, Barkhof F, Konrad RJ, Drent ML, et al. GLP-1 receptor activation modulates appetite- and reward-related brain areas in humans. Diabetes. 2014;63
- 4186-96. 12. Zhang X, Cao C, Zheng F, Liu C, Tian X. Therapeutic Potential of GLP-1 Receptor Agonists in Diabetes and Cardiovascular Disease: Mechanisms and Clinical Implications. Cardiovascular drugs and therapy. 2025.
- Kyrou I, Tsigos C, Mavrogianni C, Cardon G, Van Stappen V, Latomme J, et al. Sociodemographic and lifestyle-related risk factors for identifying vulnerable groups for type 2 diabetes: a narrative review with emphasis on data from Europe. BMC Endocrine Disorders. 2020;20(1):134.
- Preventio CfDCa. Monitoring Your Blood Sugar: CDC; 2024
- Sarah SC, Jean ML. Blood glucose, blood pressure, and cholesterol testing among adults with diabetes before and during the COVID-19 pandemic, USA, 2019 vs 2021. BMJ Open Diabetes Research & Care. 2023;11(3):e003420.
- Clark NG, Fox KM, Grandy S, Group ftSS. Symptoms of Diabetes and Their Association With the Risk and Presence of Diabetes: Findings from the Study to Help Improve Early evaluation and management of risk factors Leading to Diabetes (SHIELD). Diabetes Care. 2007;30(11):2868-73.
Disclaimer: This content is part of a disease awareness initiative by Novo Nordisk. The opinions and views are that of the Healthcare Professionals. The news and editorial staff of ET had no role in the creation of this article nor vouch for or endorse any of its content. While the content on this site provides general information about health and wellbeing. It is not intended as medical advice, nor is it a substitute for professional medical expertise or treatment. If you need help getting your health under control, we recommend speaking to your doctor.
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