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Philadelphia, Pennsylvania, United States
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Articles by Josh
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15 Rejections That Changed My Life...
15 Rejections That Changed My Life...
For high school seniors, college decision season feels like judgment day. Every acceptance feels like validation.
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39 Comments -
Happy Holidays from First Round!Dec 20, 2016
Happy Holidays from First Round!
It's the holiday season and a time for good cheer, so let's wrap up 2016 and bring in the new year. To all you startups…
157
12 Comments -
What It's Like to Lead a Startup According to 700+ FoundersDec 1, 2016
What It's Like to Lead a Startup According to 700+ Founders
Last year, we launched State of Startups to capture what it means to be an entrepreneur. We asked the leaders of…
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23 Comments -
The Watney Rule for Startups — and the Return to the ‘Old Normal’Mar 4, 2016
The Watney Rule for Startups — and the Return to the ‘Old Normal’
About a year ago, we published a quarterly letter to our limited partners — in which we talked about the risk that the…
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62 Comments -
Happy Holidays from First Round CapitalDec 17, 2015
Happy Holidays from First Round Capital
♫ ♬ The holidays are here, and our community is ready To share some cheer, even though markets are unsteady. We…
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16 Comments -
What does it mean to be a startup entrepreneur in 2015?Dec 3, 2015
What does it mean to be a startup entrepreneur in 2015?
..
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102 Comments -
10 Years of Investing, 10 Lessons Learned at First Round CapitalJul 30, 2015
10 Years of Investing, 10 Lessons Learned at First Round Capital
Ten years is a long time. When we started First Round in 2005 with the idea to fill the gap between individual angel…
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36 Comments -
Crystal Balls vs. CalculatorsJun 29, 2015
Crystal Balls vs. Calculators
There’s been a lot of conversation about the state of our industry lately. Some people caution that we’re in a “risk…
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33 Comments
Activity
26K followers
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Josh Kopelman shared thisSo impressive to see the immediate impact that HealthLeap AI is having at Penn Medicine, University of Pennsylvania Health System's. Congrats to Josiah Meyer and the entire Healthleap team!Josh Kopelman shared thisAt the Hospital of the University of Pennsylvania (HUP), Penn Medicine’s largest hospital, and a global leader in clinical nutrition, HealthLeap AI screens 100% of inpatients every day. The results they found: • Increased identification of malnutrition risk, driving a 𝟮𝟳% 𝗶𝗻𝗰𝗿𝗲𝗮𝘀𝗲 𝗶𝗻 𝗠𝗖𝗖 𝗰𝗮𝗽𝘁𝘂𝗿𝗲. • 𝟰,𝟴𝟭𝟮 𝗯𝗲𝗱-𝗱𝗮𝘆𝘀 𝘀𝗮𝘃𝗲𝗱 annually. • $𝟭𝟲.𝟭𝗠 𝗶𝗻 𝗮𝗻𝗻𝘂𝗮𝗹𝗶𝘇𝗲𝗱 𝗳𝗶𝗻𝗮𝗻𝗰𝗶𝗮𝗹 𝗶𝗺𝗽𝗮𝗰𝘁 at a single hospital site. What matters most, and resonates deeply with my team and me, are the weekly patient impact stories. Each case uniquely identified by HealthLeap represents a person who received timely, appropriate clinical nutrition care. Huge thanks to Marianne Aloupis for world-class leadership in clinical nutrition; the entire HUP registered dietitian team for setting the standard in excellence and compassion for patients every day; Edward Chen for rigorous, decision-shaping analytics; Dr. Neil Fishman for championing this work as CMO; and Dr. Regina Cunningham, whose leadership as CEO enables HUP to lead in the transformation of care.
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Josh Kopelman reposted thisJosh Kopelman reposted thisToday, Anthropic published a case study about Artemis Security. When we started this company, the thesis was simple. You can't bolt intelligence onto a fundamentally static architecture. You have to start over, with AI as the reasoning engine. What's in the post matters less than what it represents. One of the most rigorous AI labs in the world looked at how we built Artemis and decided to tell that story. 96% reduction in mean time to resolution. 90% increase in detection coverage. Investigations that used to take hours now get to resolution in under five minutes. Customers are now ready to secure themselves in the era of AI-powered attacks. We also love using Claude internally. Our team built hundreds of skills used everyday by both our people as well as our agents. Thank you to the Anthropic team for the partnership and the trust. Working closely with you allows us to deliver leading-edge AI-native defense for customers. Case study linked in the comments.
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Josh Kopelman shared thisLast November Parallel Web Systems raised their Series A. Today, they’re announcing a $100M Series B at a $2B valuation, more than doubling in five months. We invested in Parag Agrawal pre everything, no product, no customers, no revenue, just an idea that AIs will use the web 1000x more than humans ever would. Now, more than 100,000 developers are building on Parallel’s infrastructure — including customers like Harvey, Notion, Opendoor and two of the US’s leading P&C insurers. The premise Parag started with is playing out faster than any of us expected. Lucky to have been along for the ride since the beginning. Congrats to Parag and the entire Parallel team. Read about the funding in The Wall Street Journal: https://lnkd.in/gEhWt8Aw
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Josh Kopelman reposted thisJosh Kopelman reposted thisToday, we’re announcing that Manifest OS has raised a $60 million Series A at a $750M valuation to power the next generation of fully AI-native law firms. Thank you Menlo Ventures Kleiner Perkins First Round Capital and Quiet Capital for believing in this vision. After two years of hard work on this mission, I am humbled and privileged to finally share our story. Full video explaining who we are: https://lnkd.in/eGM4DEYH As an immigrant who navigated the long journey to become a US citizen, and later as an entrepreneur building companies, I experienced first hand how broken the legal system is. The billable hour makes costs unpredictable and the process slow, archaic and overwhelming. Manifest OS isn’t solving this problem by just selling AI to lawyers; we are redesigning the law firm business model from the ground up to prioritize certainty, transparency, and speed. By rebuilding the role of the attorney for the AI era, we’re making high-quality representation accessible to the 80% of businesses and consumers who currently can't afford it. We incubated the first Manifest OS powered law firm in business immigration law just over 18 months ago. Since then, we’ve seen Manifest OS scale to powering over 100 attorneys supporting more than 3,000 clients nationally, ranging from small businesses and individuals to some of the leading technology companies in America. Beyond grateful to our investors Shawn Carolan, Croom Beatty, Ilya Fushman, Bill Trenchard, Josh Kopelman, Michael Bloch, Matt Humphrey, David Greenbaum, Stewart Butterfield, Scott Belsky, Gokul Rajaram, Noah Desai Weiss, David Schellhase, A. Toby Espinosa, Zachary Smith, Guillaume "𝑮" Cabane, Micah Moreau, Michael Kives, Bryan Baum, Jason Shuman, Mike McNamara, Howard Rosenberg, and our rockstar team: Tara Neuman, James F. Cariello, Monica Desai Weiss, Avi Goldenberg, Shivanie Barapatre, Alex Shevtsov, Eric Oberman, Matt Gale, Daniel Dong, Gedalia Gillis and more. If you’re inspired by our mission, check out our open roles: https://lnkd.in/eVv5SAPz
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Josh Kopelman reposted thisJosh Kopelman reposted this“Blank check founders” are the ones I’d fund pre-idea, no matter what it is. Snir Kodesh is one of them. I’ve known him for 5+ years through our First Round Capital community: Angel Track, Eng Leaders Forum, PMF Method. His first company was acquired by Lyft, and he later went on to lead engineering at Retool. When he was ready for his next thing, we invested before he even had a specific idea. He ended up in a domain most founders wouldn’t dare touch — enterprise audit — but one he knows extremely well. Snir is deeply technical and innately commercial, a heat-seeking missile when it comes to finding a big problem and imagining the right technology to solve it. Today, Petual is coming out of stealth with $20M in funding. They’re bringing agentic AI to SOX testing, autonomously generating auditor-ready work papers in minutes instead of hours. Early customers, including S&P 500 and NASDAQ 100 companies across energy, SaaS and financial services, can see 68-80% efficiency gains on workflows that today eat hundreds of hours per quarter. $8B goes to SOX compliance in the US every year, but that’s just the start. The broader audit opportunity is massive — and to tackle both, Snir built a team of folks from Stripe, Retool, Lyft and the Big Four who understand these problems from all angles.
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Josh Kopelman shared thisShachar Hirshberg and Dan Shiebler make offers to new hires within 48 hours of their first conversation. They’re building an AI-native security company, Artemis Security, that battles threats that move at machine speed (which, for AI-driven attacks, is often in seconds). So speed is naturally an important operating principle for them. They’ve assembled a team of 30 people in NYC in under seven months, which they’ve done by front-loading references, bringing candidates in for lunch with the full team, and managing most of the recruiting process directly themselves. Engineering velocity is often a hiring problem in this market, and these guys have figured out a system that lets their recruiting process move as fast as their product. Their engineers run multiple Claude Code instances simultaneously to ship features in parallel, nearly all of their code is AI-generated, and they’ve outrun their original product roadmap by seven months. But they still haven’t managed to find any candidates who use AI as heavily as the Artemis team does. That isn’t a dealbreaker for them, though — they’re only looking for people who want to learn, and they train everyone who joins to ship as fast as the founders do. Fresh off their $70M fundraise and launch out of stealth, I sat down with Shachar and Dan on In Depth to find out how they’re pulling all of this off. We also dig into: -Why they’re on a texting basis with every CISO they sign -Why AI is a death knell for legacy security platforms -How they maintain decision-making velocity in their relationship as co-founders You can listen to our full conversation here: https://lnkd.in/gqgQgkWZ
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Josh Kopelman reposted thisJosh Kopelman reposted thisToday we’re announcing Artemis Security and our 70M Seed + Series A. I’ve spent most of my career working on machine learning systems - from my PhD at Oxford to building ML at Twitter and Abnormal. Across all of it, one thing kept coming up: AI systems only work if they actually understand the data they’re operating on. When Shachar Hirshberg and I met, we realized we were seeing the same thing in security: the systems haven’t caught up to the AI era. There’s more data than ever, but very little context. Detections don’t reflect the environment. Investigations are still manual. And attackers are moving faster than human workflows can keep up. Many teams are trying to fix this by layering LLMs on top of existing systems, but that’s not enough. The real challenge is building a robust representation of the data so models can make reliable decisions. So we stepped back and asked: what would a detection and response engine built for the AI era actually look like? Artemis models how an environment actually works - users, machines, cloud workloads, applications, and how they interact - so every detection and investigation runs on top of shared context. So instead of alerts and raw logs, you get a clear answer: what happened, why it matters, and what to do next. I’m grateful for the support we have from our investors - including Felicis, First Round Capital, Brightmind Partners, Theory Ventures, Lockstep, Two Sigma Ventures the founders of Abnormal AI and Demisto, the former CEO and CTO of Splunk, and senior executives from CrowdStrike, Palo Alto Networks, Microsoft, and Okta. I’m incredibly proud of what the team has built and the trust that our early customers have shown us. Check out https://lnkd.in/ejWSp-8W to learn more.
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Josh Kopelman reposted thisJosh Kopelman reposted thisSeven months ago, Dan Shiebler and I started Artemis Security. Today, we’re coming out of stealth with $70M in funding. The round was led by Felicis with First Round Capital and Brightmind Partners doubling down, alongside top VCs including Theory Ventures, Lockstep, Two Sigma Ventures, and prominent cybersecurity industry leaders, including the founders of Abnormal AI and Demisto, the former CEO and CTO of Splunk, and senior executives from CrowdStrike, Palo Alto Networks, Microsoft, and Okta. I spent a decade building enterprise security platforms at Demisto, Palo Alto Networks, and AWS GuardDuty. Dan led AI/ML at Abnormal AI and Twitter. Across hundreds of security teams, we kept seeing the same thing: more data than ever, and almost no way to use it to stop attacks. Detections tuned for someone else's environment. Investigations done by hand. Attackers moving faster than any human workflow can match. We built Artemis to change that. Artemis understands your environment before it starts looking for threats - modeling relationships between users, machines, cloud workloads, applications, and business context across every log source. Detections adapt to your environment. Every signal triggers an autonomous investigation that already knows your baseline. You don't get an alert and a link to raw logs. You get a story: what happened, the evidence, what was contained by Artemis, and what needs your judgment. The result: our customers have reduced their mean time to detect and respond to security events by 94%. We're in production with some of the world's largest companies across financial services, technology, and insurance, analyzing over 15,000TB daily. We are grateful for those who believed from the first moment till now and excited for what’s to come. If your security team is spending more time assembling context than making decisions, we'd love to show you what Artemis can do. Want to learn more? Visit https://lnkd.in/ejKq3zik
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Josh Kopelman shared thisHuge congrats to Shachar Hirshberg and Dan Shiebler on the launch of Artemis with a combined $70M Seed and Series A! I got the chance to sit down with Shachar and Dan to learn more about how they’re building an AI-native team at Artemis for my first time hosting the In Depth podcast. Hopefully I did okay and it’s not my last. Check out the episode when it drops next week… https://lnkd.in/d75PZJAHJosh Kopelman shared thisAnthropic Mythos is a wake-up call that the biggest threat to cybersecurity in the coming years will be AI, not humans. Legacy SIEMs were designed for human attacks. Static rules, ingest-everything architectures, thousands of daily alerts, and most of them false positives. With this system, security teams can only respond to events after the fact, and that’s not going to cut it to protect against bad actors with astoundingly good tech. Shachar Hirshberg and Dan Shiebler aren’t new to this fight. I first got to know Shachar when he came to First Round’s PMF Method program in 2024. I was immediately struck by how deep he’d gone in security: He was an early engineer at Demisto, the company that defined the SOAR category and was acquired by Palo Alto Networks, and he later led product management for Amazon GuardDuty. And Dan’s been waging an AI vs. AI war his entire career. He led ML at Twitter when the opponent was spam bots and scams, and he saw the first rumblings of how AI could undermine the existing security architecture while he was Head of AI/ML at Abnormal Security. Instead of tacking agents onto the old systems, they saw an opportunity to build a platform that helps security teams battle AI with AI. I’m so excited for Shachar and Dan to officially launch Artemis Security today with $70M in combined Seed and Series A funding, with Felicis leading the Series A and First Round Capital and Brightmind Partners leading the Seed. Artemis is an AI-native protection platform that builds a model of how your organization actually operates. Instead of just pinging analysts with constant alerts with zero context, it gives security teams what it calls “attack stories” so they can understand who the users are and how to respond. I first invested in Shachar and Dan last year when it was just the two of them and a very early idea. What they’ve built in seven months since founding is off the charts: The platform processes billions of events per hour, they've already closed big enterprise logos, nearly 100% of their code is AI-generated, and they've outrun their original product roadmap by 8 months. Artemis is one of only a handful of cybersecurity startups working with Anthropic directly to build Claude’s reasoning into the product to make their detection even smarter. Great writeup from Sharon Goldman in Fortune today: https://lnkd.in/gcu3RPW2 And more on what Shachar and Dan are building with Artemis: https://lnkd.in/gWsGaeqA Here’s a sneak peek of my Partner Josh Kopelman sitting down with Shachar and Dan to find out what it takes to build a truly AI-native team and product on an upcoming episode of In Depth. Stay tuned for the episode dropping next week 👀
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Daniel Dart
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Matt Rappaport
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Here's a counterintuitive truth: if you get sued for patent infringement, you should consider yourself lucky. It means you've built something valuable enough that competitors are worried. Most founders swing between two extremes: IP naive (ignoring patents completely) or IP obsessed (building patent fortresses instead of businesses). Both kill startups. After 20+ years in IP strategy, investing in deep tech startups, and now building a deep tech startup accelerator, I've seen the pattern repeatedly. The founders who succeed understand patents as competitive intelligence tools and business enablers—not substitutes for finding customers. New post breaks down the IP strategy spectrum and why the sweet spot matters more than most founders realize. 👉 https://lnkd.in/g2x5ssyJ
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Earnest Sweat
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Austin Walters
SpringTide Ventures • 13K followers
I met Craig Limoli, Founder and CEO of Wellsheet, in 2019. Craig was presenting at the Ai4 Healthcare Conference in New York City, hosted by Michael J Weiss . It was one of those early gatherings focused on AI in healthcare - well before the recent wave of hype. Craig took the stage to share how Wellsheet was using AI to help doctors and nurses make better, faster decisions at the point of care with its Care Team Copilot. Wellsheet’s technology was impressive, but its real edge came from Craig’s deep understanding of the problem he was solving. Before founding Wellsheet, he worked at IBM as a strategy consultant, helping large health systems assess their tech stacks. He saw firsthand that the tools available were clunky, fragmented, and ultimately failed to support the clinicians doing the hardest work. It’s a story as old as time - the very systems IBM was selling to hospitals weren’t meeting their actual needs. So, Craig left IBM, enrolled in the The Wharton School MBA program to sharpen his entrepreneurial skills, and decided to build the product those systems truly needed - a Care Team Copilot designed to summarize patient charts, streamline documentation, and support real-time collaboration between physicians and nurses. We stayed in touch after that first meeting, and a few months later, Wellsheet raised its $4.5 million Series A, which our team at SpringTide Ventures led. The round came together just as the world was shutting down in the early months of the pandemic. Understandably, Craig was nervous that investors might pull back as uncertainty swept through the market, but we didn’t. We believed in Wellsheet’s mission, and more importantly, in Craig’s ability to execute against it. Despite the chaos of 2020, he stayed focused and transparent - qualities that made us even more confident we were backing the right founder at the right time. Fast forward to today: Wellsheet is now live at hundreds of hospitals and continues to outperform much larger competitors. In fact, when a major national health system evaluated solutions from both Google and Wellsheet, they unanimously chose Wellsheet. The healthcare industry faces an unprecedented shortage of doctors, nurses, and frontline clinicians. Wellsheet’s technology helps address this challenge by automating the most time-consuming and manual parts of clinical work. For physicians, it means no more laborious data entry; for executives, it means decisions are queued up for them - clear, informed, and ready to act on. By streamlining chart reviews, documentation, and decision support, Wellsheet enables care teams to focus on what truly matters: delivering better patient outcomes. We’re proud to support, and keep championing founders like Craig and his mission-driven team at Wellsheet!
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Salesfully.com
2K followers
Startups don’t need VC to grow. Revenue-based financing doubled from $1.8B in 2021 to over $3.8B in 2024 and average deals are ~$350k with a 6% cap. Funding mix in 2025: VC 52%, crowdfunding 14%, RBF 11%, angels 10%, partnerships 7%, grants 6%. 1,500 companies raised $700M via crowdfunding in 2023. Explore smarter funding options: https://lnkd.in/ebTeA_MX #StartupFunding #AlternativeFinance
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Dave Lu
Hyphen Capital • 47K followers
I’m so proud that Hyphen Capital has been a backer of Tim Hwang and Jonathan Chen since the beginning of Nitra. They had big ambitions to modernize the archaic back office of healthcare practices from fax machines to AI. It’s been amazing to see their growth from processing zero transactions to over a billion dollars and they’re just getting started.
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Medha Agarwal
defy.vc • 16K followers
I’m thrilled to announce defy.vc’s investment in Birches Health as part of their $20M combined Seed and Series A funding round, alongside incredible partners like AlleyCorp, General Catalyst, Will Ventures, and others. As someone deeply passionate about backing companies that tackle important problems for our society, I couldn’t be more excited about what Birches is building—a national virtual clinic dedicated to treating gambling addiction and related behavioral disorders like gaming, sex, porn, and internet addictions. What excites me most is Birches’ innovative health assurance model: proactive, accessible, and affordable care that’s evidence-based and delivered right at home. With the explosion of legal sports betting—think nearly $1.5 billion wagered on this year’s Super Bowl alone—we’re staring down a looming public health emergency. Traditional options like hotlines or generic therapy fall short for this high-acuity issue, but Birches changes that by offering specialized therapy from trained clinicians, multimodal treatment, and peer support, all covered by major insurers like United Healthcare, Cigna, Aetna, and Blue Cross Blue Shield. It’s available in all 50 states, breaking down geographical and financial barriers that have left so many without help. The impact is already profound: 96% of patients report an improved quality of life, and 94% give Birches a 5/5 rating. By partnering with state governments, payors, and policymakers, Birches is pushing gambling addiction into the spotlight of behavioral health conversations, where it’s been neglected for too long—often leading to shame, worsened outcomes, and higher suicidality risks. This funding will supercharge their growth: expanding the provider network, boosting clinical excellence, scaling infrastructure, and deepening insurance and state partnerships to meet surging demand. Very excited to partner with Elliott Rapaport and the entire Birches team! See more about our POV in the blog post linked in the comments. #GamblingAddiction #BehavioralHealth #HealthTech #VentureCapital #Innovation
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Edgar Chiu
Camp Mobile • 10K followers
🚀𝐇𝐮𝐠𝐞 𝐦𝐢𝐥𝐞𝐬𝐭𝐨𝐧𝐞 𝐟𝐨𝐫 𝐍𝐢𝐭𝐫𝐚 𝐚𝐧𝐧𝐨𝐮𝐧𝐜𝐢𝐧𝐠 𝐭𝐡𝐞𝐢𝐫 $𝟏𝟖𝟕𝐌 𝐟𝐢𝐧𝐚𝐧𝐜𝐢𝐧𝐠. I first met Jonathan in 2021, and SparkLabs Taiwan became a seed investor in Nitra in 2022. From the beginning, the team had a bold vision to build an operating system for healthcare. Along the way, we’ve been supporting Nitra in building its engineering footprint in Taiwan, and we also had the chance to introduce new investors who later joined this round. Proud to have supported this journey from the early days. Excited for what’s ahead! 🚀 [Tim Hwang Hsufeng Lee Bernard Moon SparkLabs Group Eugene Kim Mallory Chien Regina Lo Kenny Chen]
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Andrew Grechkin
PaxRide • 3K followers
The dorm room startup era is officially over. 🏠 Crunchbase, after analyzing 800+ recent seed rounds, identified four trends dominating 2025: longevity, defense tech, waste reduction, and spacetech. We're talking about companies developing gene therapy to restore aged cells, whole-body cryopreservation, next-gen munitions manufacturing, and spacecraft propulsion systems. The numbers: - Defense tech startup Amca: $76.5M seed from A16z, Founders Fund, Lux Capital - Union Technologies: $50M for high-tech defense manufacturing - Spacetech collectively: $35B+ since 2021 Unlike the dot-com boom or app economy rise, today's hot seed investments require enormous expertise just to launch. You can't build spacecraft propulsion or develop life-extending therapies in a dorm room. This represents a fundamental shift in startup capital—from "move fast and break things" to "move precisely and extend things." The future we're funding: longer lives in well-fortified locations with actual recycling, under skies crowded with sophisticated satellites. Are we witnessing the maturation of venture capital, or just the natural evolution toward harder problems? #VentureCapital #SeedFunding #Longevity #DefenseTech #Spacetech #StartupTrends
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Shahid Azim
C10 Labs • 18K followers
C10 Labs Expanding into the New England AI and innovation ecosystem! C10 Labs and RIHub have partnered to accelerate the growth of applied AI startups across Massachusetts and Rhode Island. The collaboration provides early-stage founders with shared resources, accelerator support, investor access, and mentorship in sectors like applied at the intersection of core sectors like health, energy, climate, biotech, and robotics. #AI #Startups #Innovation #NewEngland #VentureCapital. David Berlin Patricia Geli Beth Porter Marissa Flanagan
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